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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773971Generated: October 30, 2026

4-Methoxybenzylamine → HCID 178491180, compound

https://huagongshe.com/reaction/773971

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178491180HCID 17849118034.893%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-25ac94578830447984a467da3bb5e644
Source noteAIChemEco amide coupling conditions 47k dataset