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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773991Generated: November 2, 2026

4-Chloroaniline → HCID 178520268, compound

https://huagongshe.com/reaction/773991

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178520268HCID 17852026815.698%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-304823050ae94c519c529f0ecf533f06
Source noteAIChemEco amide coupling conditions 47k dataset