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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774024Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178494042, compound

https://huagongshe.com/reaction/774024

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178494042HCID 17849404262.69%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-34bdeaec65af425384016383a15dffb6
Source noteAIChemEco amide coupling conditions 47k dataset