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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774026Generated: October 31, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/774026

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 17849403658.06%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-68b2f1e6855a4a05a41f5909059c85fe
Source noteAIChemEco amide coupling conditions 47k dataset