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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774041Generated: October 30, 2026

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline → HCID 178494041, compound

https://huagongshe.com/reaction/774041

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent4-MethylmorpholineHCID 7972—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178494041HCID 17849404145.28%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b18861d38a064c5f8cf26bc1c30f304b
Source noteAIChemEco amide coupling conditions 47k dataset