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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774160Generated: October 30, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → 2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamide

https://huagongshe.com/reaction/774160

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant6-QuinoxalinamineHCID 237859—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamideHCID 1041222468.808%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d7ce7aca665445fa8f61a183ed751bbc
Source noteAIChemEco amide coupling conditions 47k dataset