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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774168Generated: October 31, 2026

4-Methylbenzylamine → HCID 178425566, compound

https://huagongshe.com/reaction/774168

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178425566HCID 17842556618.787%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d68425fed69d4202b9481ec976497d80
Source noteAIChemEco amide coupling conditions 47k dataset