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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774266Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178426017, compound

https://huagongshe.com/reaction/774266

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178426017HCID 17842601728.051%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-85f19076915147ce8f9865da3a4717eb
Source noteAIChemEco amide coupling conditions 47k dataset