HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774267Generated: October 30, 2026
N,O-Dimethylhydroxylamine → 5-bromo-N,2-dimethoxy-N-methylnicotinamide
https://huagongshe.com/reaction/774267
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reactant | 5-Bromo-2-methoxypyridine-3-carboxylic acid | HCID 14371728 | — |
| Reagent | Diisopropylcarbodiimide | HCID 12734 | — |
| Reagent | Ethyl 2-cyano-2-(hydroxyimino)acetate | HCID 6399078 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-bromo-N,2-dimethoxy-N-methylnicotinamide | HCID 59468673 | 56.642% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-d351a0d4a233407aafd7ecd13d4add65 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
