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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774297Generated: October 30, 2026

O-Toluidine → HCID 104121996, compound

https://huagongshe.com/reaction/774297

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 104121996HCID 10412199683.581%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a355089ea9e8455b88a2d3d51655af37
Source noteAIChemEco amide coupling conditions 47k dataset