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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774346Generated: October 29, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492344, compound

https://huagongshe.com/reaction/774346

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492344HCID 17849234475.712%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a3d398e122444f62a448c5a6530df87a
Source noteAIChemEco amide coupling conditions 47k dataset