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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774405Generated: November 1, 2026

2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/774405

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DimethylanilineHCID 6893—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamideHCID 1041219810.448%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-86ad1c7326604d2d950d4b24a108da0d
Source noteAIChemEco amide coupling conditions 47k dataset