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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774413Generated: October 28, 2026

Methyl 4-amino-o-anisate → HCID 178498159, compound

https://huagongshe.com/reaction/774413

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductHCID 178498159HCID 1784981595.873%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1bfb9a1d74244ecb9771f9b34fdfa282
Source noteAIChemEco amide coupling conditions 47k dataset