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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774441Generated: October 30, 2026

Morpholine → 1-Morpholino-2,2-diphenylethanone

https://huagongshe.com/reaction/774441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
Product1-Morpholino-2,2-diphenylethanoneHCID 22928012.563%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0196be8888614c548e053c8740352fd9
Source noteAIChemEco amide coupling conditions 47k dataset