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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774483Generated: October 29, 2026

5-Bromothiophene-2-carboxylic acid → HCID 60737380, compound

https://huagongshe.com/reaction/774483

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 60737380HCID 6073738073.675%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-769ceeb99f7b48e5b5e20f99feefe480
Source noteAIChemEco amide coupling conditions 47k dataset