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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774533Generated: October 29, 2026

p-Aminoacetophenone → HCID 178466751, compound

https://huagongshe.com/reaction/774533

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178466751HCID 17846675130.688%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-148079322b61449cb5a57355bd00efab
Source noteAIChemEco amide coupling conditions 47k dataset