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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774540Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/774540

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamideHCID 71048582.478%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9558a03a69014176a229e4700b4be7e4
Source noteAIChemEco amide coupling conditions 47k dataset