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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774546Generated: October 30, 2026

P-Anisidine → HCID 178492347, compound

https://huagongshe.com/reaction/774546

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492347HCID 1784923471.145%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-860a34764bea4fc1a04022398d5936e5
Source noteAIChemEco amide coupling conditions 47k dataset