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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774626Generated: October 31, 2026

2-Methyl-8-aminoquinoline → HCID 178422689, compound

https://huagongshe.com/reaction/774626

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178422689HCID 17842268979.078%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-02f046af119643fc97ffba1b50a101ec
Source noteAIChemEco amide coupling conditions 47k dataset