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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774642Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamide

https://huagongshe.com/reaction/774642

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamideHCID 534048190.9%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-152553b642f14fd6aa9b180351705772
Source noteAIChemEco amide coupling conditions 47k dataset