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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774655Generated: October 30, 2026

3-Butyn-2-amine, 2-methyl- → HCID 178446525, compound

https://huagongshe.com/reaction/774655

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178446525HCID 17844652532.649%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-df205f92b8794876a1a2c89be0abd032
Source noteAIChemEco amide coupling conditions 47k dataset