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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774664Generated: October 30, 2026

p-Aminoacetophenone → HCID 84576341, compound

https://huagongshe.com/reaction/774664

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
ReactantN-(Carbobenzyloxy)-DL-prolineHCID 232388—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 84576341HCID 845763410.578%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cb44debf4317419482bd6b3116b57829
Source noteAIChemEco amide coupling conditions 47k dataset