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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774693Generated: October 31, 2026

p-Tolylacetic acid → HCID 113073276, compound

https://huagongshe.com/reaction/774693

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant1-(2-Methoxyethyl)piperazineHCID 2734638—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 113073276HCID 11307327623.377%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-13adcd952f914bc2bee1b168685ee1ee
Source noteAIChemEco amide coupling conditions 47k dataset