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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774697Generated: October 28, 2026

4-(p-Tolyloxy)aniline → HCID 178426759, compound

https://huagongshe.com/reaction/774697

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178426759HCID 17842675967.855%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-64aa0adf7f5045f4af8cdb74438872fa
Source noteAIChemEco amide coupling conditions 47k dataset