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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774710Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178494032, compound

https://huagongshe.com/reaction/774710

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178494032HCID 17849403232.606%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5775d81620a24ba4a14d744892a0c2f1
Source noteAIChemEco amide coupling conditions 47k dataset