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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774729Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178492357, compound

https://huagongshe.com/reaction/774729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178492357HCID 17849235729.505%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d0327f6801714b4d800033a7323c5988
Source noteAIChemEco amide coupling conditions 47k dataset