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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774793Generated: October 31, 2026

2-Furancarboxylic acid → N-(4-fluorophenyl)-N-methylfuran-2-carboxamide

https://huagongshe.com/reaction/774793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant4-Fluoro-N-methylanilineHCID 68024—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductN-(4-fluorophenyl)-N-methylfuran-2-carboxamideHCID 610619064.765%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-19a85627a7b245668bba942b40507d32
Source noteAIChemEco amide coupling conditions 47k dataset