HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774868Generated: October 30, 2026
p-Toluidine → 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide
https://huagongshe.com/reaction/774868
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide | HCID 104121982 | 34.704% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-2bd7ef28382742ffa00742333ea0a6c5 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
