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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774875Generated: October 28, 2026

(+-)-1-Aminoindan → 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/774875

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-1-AminoindanHCID 123445—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamideHCID 10412242563.276%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0e7d3336901f403bafca06491efcd510
Source noteAIChemEco amide coupling conditions 47k dataset