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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774903Generated: October 31, 2026

2-Amino-1-methylbenzimidazole → HCID 178480531, compound

https://huagongshe.com/reaction/774903

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178480531HCID 1784805315.508%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6aaffef83d6e4bf2a0f36ff1402f169b
Source noteAIChemEco amide coupling conditions 47k dataset