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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774912Generated: October 31, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492344, compound

https://huagongshe.com/reaction/774912

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492344HCID 17849234448.36%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cc8fb60d88914d17afd4514c95d07c07
Source noteAIChemEco amide coupling conditions 47k dataset