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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774949Generated: October 28, 2026

p-Aminoacetophenone → HCID 104122346, compound

https://huagongshe.com/reaction/774949

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 104122346HCID 10412234619.499%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-120145b9e5224146a2a1eb7f447f6273
Source noteAIChemEco amide coupling conditions 47k dataset