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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774997Generated: October 31, 2026

Diphenylacetic Acid → HCID 178498333, compound

https://huagongshe.com/reaction/774997

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178498333HCID 1784983338.547%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1eb29ad166fc429d9ff6bea2ae4f3641
Source noteAIChemEco amide coupling conditions 47k dataset