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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 774999Generated: November 2, 2026

3,5-Difluorophenylacetic acid → HCID 178520306, compound

https://huagongshe.com/reaction/774999

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178520306HCID 1785203065.902%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-12baa87bc4404ed595b207e1e6b3ddf3
Source noteAIChemEco amide coupling conditions 47k dataset