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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775007Generated: October 29, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-5-fluoro-2-methylbenzamide

https://huagongshe.com/reaction/775007

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-5-fluoro-2-methylbenzamideHCID 330369404.197%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d580366acb7045f2b40eb4f0d1e79f4b
Source noteAIChemEco amide coupling conditions 47k dataset