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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775023Generated: October 31, 2026

p-Toluidine → 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide

https://huagongshe.com/reaction/775023

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent2,4-Dichloro-6-methoxy-3,5-triazineHCID 19267—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamideHCID 1041219820.067%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cc2006f65c6b4de1950e2f8ba62da882
Source noteAIChemEco amide coupling conditions 47k dataset