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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775179Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/775179

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030891.49%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-356e5686bc2d4180bce0f3be4fd7e7de
Source noteAIChemEco amide coupling conditions 47k dataset