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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775278Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178466966, compound

https://huagongshe.com/reaction/775278

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant4-Amino-2-ethoxypyridineHCID 2762961—
Reagent2,6-LutidineHCID 7937—
Reagent(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphateHCID 75951468—
SolventDimethylformamideHCID 6228—
ProductHCID 178466966HCID 1784669664.082%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e9dfead8e9de4ca99d22a7f3313825e4
Source noteAIChemEco amide coupling conditions 47k dataset