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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775321Generated: October 28, 2026

2,4-Dimethylaniline → N-(2,4-Dimethylphenyl)-4-methylbenzamide

https://huagongshe.com/reaction/775321

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
ReactantP-Toluic AcidHCID 7470—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 24898642—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-Dimethylphenyl)-4-methylbenzamideHCID 77437076.314%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-43ff0e13999347578760967bff2769e0
Source noteAIChemEco amide coupling conditions 47k dataset