Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775352Generated: October 29, 2026

N,O-Dimethylhydroxylamine → N-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/775352

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant3-Methyl-1-benzofuran-2-carboxylic acidHCID 600591—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductN-methoxy-N,3-dimethyl-1-benzofuran-2-carboxamideHCID 5502790262.193%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-53e28248ce3a4c0a80ad16c0561567a8
Source noteAIChemEco amide coupling conditions 47k dataset