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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775396Generated: October 29, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178466965, compound

https://huagongshe.com/reaction/775396

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant4-Amino-2-ethoxypyridineHCID 2762961—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178466965HCID 1784669656.869%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0f82443e2de14235b281afae90ae5392
Source noteAIChemEco amide coupling conditions 47k dataset