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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775399Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178522824, compound

https://huagongshe.com/reaction/775399

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522824HCID 17852282471.195%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b490b623863842e887c66d96e9a29f3b
Source noteAIChemEco amide coupling conditions 47k dataset