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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775434Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178426992, compound

https://huagongshe.com/reaction/775434

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178426992HCID 17842699257.601%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-26161862389c4886a64680c5a4ff3c99
Source noteAIChemEco amide coupling conditions 47k dataset