反应详情

tert-Butyl 3-(2-(2-hydroxyethoxy)phenyl)-3-oxopropanoate (2.0 g, 7.14 mmol) in ethanol (20 mL) was heated in a microwave reactor at 120° C. for 90 min. The mixture was cooled to room temperature and the solvent was concentrated under reduced pressure to give a yellow oil. The crude product was purified by flash chromatography (30-40% EtOAc: petroleum ether) to give the title compound as a yellow solid.

1. concentrationthe solvent was concentrated under reduced pressure
2. customto give a yellow oil
3. customThe crude product was purified by flash chromatography (30-40% EtOAc: petroleum ether)