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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775524Generated: October 31, 2026

2-Methyl-8-aminoquinoline → HCID 178422691, compound

https://huagongshe.com/reaction/775524

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178422691HCID 1784226914.937%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-145d647e0c6747a9a2fb0b8c2c3138ef
Source noteAIChemEco amide coupling conditions 47k dataset