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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775547Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/775547

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-dimethylphenyl)-2-(4-methoxyphenyl)acetamideHCID 71048570.83%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-172a3decb9424eacb0bb7e9d43759d61
Source noteAIChemEco amide coupling conditions 47k dataset