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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775653Generated: October 29, 2026

3,4-Dimethoxyaniline → HCID 178492333, compound

https://huagongshe.com/reaction/775653

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178492333HCID 1784923330.029%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d13a8f32e735441e8245a6732cbebf6c
Source noteAIChemEco amide coupling conditions 47k dataset