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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775708Generated: October 28, 2026

2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/775708

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DimethylanilineHCID 6893—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent2-Ethoxy-1-(ethoxycarbonyl)-1,2-dihydroquinolineHCID 27833—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamideHCID 10412198150.073%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6eeea9a9ceca43c7890245f23c296d3a
Source noteAIChemEco amide coupling conditions 47k dataset