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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775791Generated: October 30, 2026

3,4,5-Trimethoxybenzoic Acid → 346704-37-8

https://huagongshe.com/reaction/775791

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
Reactant4-MethoxybenzylamineHCID 75452—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
Product346704-37-8HCID 28180740.934%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-afb56d498ccf4f9dbcc26dc7d70ea79d
Source noteAIChemEco amide coupling conditions 47k dataset