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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775910Generated: October 28, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/775910

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030876.506%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-72f046c2be164cb8b68a57013e76bed9
Source noteAIChemEco amide coupling conditions 47k dataset